This study, published in Ophthalmic Surgery, Lasers and Imaging Retina, was conducted to evaluate the utility of ultra-widefield fluorescein angiography (UWFFA) in children under 13. Theretrospective case series examined images from 16 patients (mean age 9.3 years) who were seen for a variety of pediatric retinal conditions, including uveitis, hereditary retinal dystrophies, retinal vascular diseases, trauma, infection, and tumors. In these patients, UWFFA revealed abnormal peripheral angiographic findings in 12 of the 16 subjects (75%). UWFFA imaging of the macula and periphery provided important information for documentation, diagnosis, and management.

Tsui I, Franco-Cardenas V, Hubschman JP, Schwartz SD. Pediatric retinal conditions imaged by ultra wide field fluorescein angiography. Ophthalmic Surgery, Lasers and Imaging Retina. 2013: 44: 59-67.

Optos UWF™ image of the right eye of a 41 week old infant who had persistent threshold disease (stage 3 zone 2 ROP with plus disease) despite previous laser therapy.